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The role of comorbidities in the associations between air pollution and Alzheimer’s disease: A national cohort study in the American Medicare population

February 17, 2026

The role of comorbidities in the associations between air pollution and Alzheimer’s disease: A national cohort study in the American Medicare population

In a national cohort study of US Medicare beneficiaries, Yanling Deng and colleagues investigate the association between air pollution and Alzheimer's Disease, examining hypertension, stroke, and depression as comorbidities that might mediate or modify this relationship.

Image credit: Mike Marrah, unsplash

02/17/2026

Perspective

Can generative artificial intelligence enhance evidence-based and personalized medicine?

In this Perspective, Arun Thirunavukarasu discusses a recent PLOS Medicine study comparing generative artificial intelligence (GAI) treatment recommendations with physicians', raising the question of whether GAI should be designed to follow treatment guidelines rigidly, provide individualized recommendations, or be somewhere in between.

Image credit: Nahrizul Kadri, unsplash

Can generative artificial intelligence enhance evidence-based and personalized medicine?

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PLOS Medicine | ISSN: 1549-1676 (online)