Archive for 23andMe

Nature tidbits [06 Feb 2025]

Posted in Statistics with tags , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , on March 10, 2025 by xi'an

Entries about the scary rise in H5N1 risks of a human transmission, compounded by Trump’s America leaving WHO, hence the US connection with global monitoring and its substantial funding of the organization. Advising against drinking raw milk as a primary precaution. Even camembert?!

A (naïve, imho) call by the presidente of the Union of Concerned Scientists to boost scientific integrity to protect (US) federal research despite the chainsaw massacre unfolding daily in (US) federal agencies. And the disregard of said massacrers for accountability and legal boundaries. And unions, definitely unions.

Also entries (and two Nature collections) on the one hundredth anniversary of the Taung Child fossil uncovering, as the first Australophitecus africanus  that opened the way for the theory that Africa was the birthplace of humanity, along with other extended books reviews. On quantum theory (it’s complicated!, according to Sean Carroll) and Kepler mission (by Jason Steffen). And a show at Cité des Sciences in La Villette about silence that I would love to attend.

A quick assessment of deepseek against its competitors. Mostly praising its open code. And another one on 23andMe losses and trouble,  reflecting the one-shot strategy of the company that cannot sell its analysis more than once (despite repeatedly trying, as I can confirm from their frequent emails). And opening concerns about their data or rather our data. Since there is very little protection in the US for this kind of data, considered out of healthcare.

New challenges of large carnivores in Western Europe, with a rise of wolverines, success story for the Iberian lynx, talks of reintroducing wolves to Scotland (to cull red deer like those who roam Buachaille Mor), degrading setting in France with looser rules for shooting wolves.

Microplastics in the brain, unsurprisingly increasing the chances of clots and surprisingly easily moving into blood vessels and the brain. And, speakiMicroplastics in the brainng of plastic, recycling, at last? Warwick Manufacturing Group (WMG) mentioned as evaluating the life-cycle analysis of a new approach with superheated water. Exposing the elephant in the room, namely that there is very little true recycling going on and that part of the recycled plastic ends up as fuel, hence contributing to pollution. Costs and impact of turning used products into new material are mentioned (and staggering albeit not compared with the initial costs and impact.

And I remain perplexed by the Two-Eyed Seeing Indigenous perspective for neuroscience article. As I do not see the scientific component, besides directions to work with local communities.

39% anglo-irish!

Posted in Kids, Statistics, Travel with tags , , , , , , , , on May 24, 2015 by xi'an

As I have always been curious about my ancestry, I made a DNA test on 23andMe. While the company no longer provides statistics about potential medical conditions because of a lawsuit, it does return an ancestry analysis of sorts. In my case, my major ancestry composition is Anglo-Irish!  (with 39% of my DNA) and northern European (with 32%), while only 19% is Franco-German… In retrospect, not so much of a surprise—not because of my well-known Anglophilia but—given that my (known, i.e., at least for the direct ancestral branches) family roots are in Normandy—whose duke invaded Britain in 1056—and Brittany—which was invaded by British Celts fleeing Anglo-Saxons in the 400’s.  What’s maybe more surprising to me is that the database contained 23 people identified as 4th degree cousins and a total of 652 relatives… While the potential number of my potential 4th degree cousins stands in the 10,000’s, and hence there may indeed be a few ending up as 23andMe—mostly American—customers, I am indeed surprised that a .37% coincidence in our genes qualifies for being 4th degree cousins! But given that I only share 3.1% with my great⁴-grandfather, it actually make sense that I share about .1% to .4% with such remote cousins. However I wonder at the precision of such an allocation: could those cousins be even more remotely related? Not related at all? [Warning: All the links to 23andMe in this post are part of their referral program.]